The Effect of Metformin upon Spermatogenesis in Mice

Document Type : Original Article

Authors

Department of genetics, faculty of agriculture,Alexandria unniveristy.

Abstract

The effect of the drug Metformin has been studied, employing Mice genome ( mus musculus 2n=40) . Three doses 250, 500 and 1000 mg/ml in addition to the negative control were tested. The results obtained has now been reported for the first time; since a significant increases in sperms 10 fold-increases were obtained. It seems probable that such effect might be caused by enhancement of cell division.
 

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